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This program is in the research and development phase and has not been approved by the FDA or any other regulatory body. The initial drug we are studying using our microcatheters is fulvestrant. Please upgrade your browser or activate Google Chrome Frame to improve your experience. The data from the Phase 1 study demonstrate the suitability gambling online casino olg topical Endoxifen for further clinical development. Of the 30 patients required for full enrollment, six will receive the standard intramuscular injection of fulvestrant and 24 will receive fulvestrant with our microcatheter device. Topical Endoxifen was well tolerated at each dose level and for the dosing duration utilized in the study. The study will be conducted at Stockholm South General Hospital in Gambling online casino olg and will be led by principal investigator Dr. We are also evaluating endoxifen in the neo-adjuvant setting, meaning it would be use to treat breast cancer before surgery remove the cancerous tumor. To date, 30 U. Fulvestrant is FDA-approved for metastatic breast cancer. Endoxifen Endoxifen is the most active metabolite ingredient of the FDA-approved drug tamoxifen, which has been used since gambling online casino olg approval in for breast cancer survivors to prevent recurrence as well as the development of new cancer. We believe our patented intraductal microcatheter technology may be useful in delivering a number of drugs directly to the breast gambling online casino olg. Although oral tamoxifen has been shown to reduce MBD, the benefit-risk ratio is generally not acceptable source most physicians and their patients. In mid we completed a Phase 1, placebo-controlled study of our proprietary topical Endoxifen. It is administered as a monthly intramuscular injection of two injections, typically into the buttocks. Typically, these receptors are used to graft the specificity of a monoclonal antibody onto a T cell, with transfer of their coding sequence facilitated by retroviral vectors. The topical formulation of our proprietary endoxifen is being developed for women with a condition call mammographic breast density, or MBD, which has been shown in third-party studies to result in a higher risk of developing breast cancer. In mid we completed a Phase 1 clinical study which was conducted by a leading Clinical Research Organization in Australia. We are currently conducting a Phase 2 study using our microcatheter technology to deliver fulvestrant at Montefiore Medical Center.

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We currently have four programs underway: two using our proprietary endoxifen (oral and topical formulations) and two using our patented microcatheter technology.
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